TRANSLATIONAL RESEARCH SOLUTIONS
One platform
from mechanism to response
Foli-seq™ provides non-invasive host gut transcriptomic readouts for research and translational teams studying intestinal mechanism, mucosal biology, and treatment response across preclinical, clinical, and cohort studies.
MECHANISM & DISEASE BIOLOGY
Map host gut pathways
Measure epithelial, immune, barrier, inflammatory, and remodeling signals to understand how intestinal biology changes with disease or perturbation.
BIOMARKER DISCOVERY
Find response-linked signatures
Identify host transcriptomic patterns associated with disease activity, pharmacodynamic effects, patient heterogeneity, or treatment response.
LONGITUDINAL MONITORING
Track mucosal response over time
Use longitudinal stool samples to track host gut biology across intervention, disease activity, or clinical response without repeated biopsy.
TRANSLATIONAL USE CASES
Host gut transcriptomics for translational research
Foli-seq™ provides non-invasive host gut transcriptomic readouts for studies where mucosal biology is central to disease mechanism, therapeutic response, microbiome intervention, or patient heterogeneity. Routine stool sampling enables longitudinal host-response profiling without repeated endoscopy.
Longitudinal response profiling
Track host gut transcriptomic changes across treatment, intervention, perturbation, or disease progression.
Responder biology
Identify host gut transcriptomic differences associated with response, non-response, disease activity, or clinical phenotype.
Patient stratification
Use baseline host gut transcriptomic profiles to stratify cohorts by mucosal biology state, disease subtype, risk, or predicted response.
Mechanism-of-action studies
Characterize how disease, perturbation, or intervention modulates immune activation, barrier function, and epithelial response.
Preclinical-to-clinical translation
Use matched human and murine Foli-seq™ panels to compare host transcriptomic signals across animal models and human studies.
Microbiome interventions
Measure the host gut response to microbiome-mediated interventions — not just changes in microbial composition.
Explore a study or partnership
We work with pharma, biotech, academic, and clinical research teams applying host gut transcriptomics to biomarker discovery, mechanistic studies, and longitudinal response monitoring.